1. Home
  2. Find a cruise
  3. American Cruise Line cruises

American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

Your search Clear selections

Any Destination
All Sail Months
Any Length
Any Port
American Cruise Line
Any Ship

Close

125 cruises found

Filters Save search

Sort by

Filter by

More
Save search

Ports

  • ST. PETERSBURG, FLORIDA
  • FORT MYERS, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - FORT MYERS, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - View more ports

American Legend S

2024 sail dates: Dec 23,

2025 sail dates: Jan 06, Jan 13, Jan 20, Jan 27, Feb 03, Feb 10, Feb 17, More

$6995*
$999/night*
Balcony
View Deal
$6995* dreamvacations.com $6995* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$7415*

$9875*

See Offers

N/A

N/A

$7415*

$9875*

 

N/A

N/A

$7415*

$9875*

See Offers

N/A

N/A

$7415*

$9875*

 

N/A

N/A

$7415*

$9875*

See Offers

N/A

N/A

$7415*

$9875*

Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05, Apr 19, May 03, May 17, More

$5275*
$754/night*
Balcony
View Deal
$5275* dreamvacations.com $5275* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5495*

$7790*

See Offers

N/A

N/A

$5495*

$7790*

 

N/A

N/A

$5495*

$7790*

See Offers

N/A

N/A

$5495*

$7790*

 

N/A

N/A

$5495*

$7790*

See Offers

N/A

N/A

$5495*

$7790*

 

N/A

N/A

$5495*

$7790*

See Offers

N/A

N/A

$5495*

$7790*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 28

2025 sail dates: Feb 15, Mar 01, Mar 15, Mar 29, Apr 26, May 10, Nov 15, Nov 29, Dec 13, Dec 27, More

$6245*
$892/night*
Balcony
View Deal
$6245* dreamvacations.com $6245* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6245*

$8565*

See Offers

N/A

N/A

$6245*

$8565*

 

N/A

N/A

$6245*

$8565*

See Offers

N/A

N/A

$6245*

$8565*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6995*

$9315*

See Offers

N/A

N/A

$6995*

$9315*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American Harmony S

5.0
(6 Reviews)

2024 sail dates:

2025 sail dates: May 03, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 09, Aug 23, Sep 20, Oct 04, Oct 18, Nov 01, More

$5595*
$799/night*
Balcony
View Deal
$5595* dreamvacations.com $5595* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 6 American Harmony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5595*

$7890*

See Offers

N/A

N/A

$5595*

$7890*

 

N/A

N/A

$5955*

$8385*

See Offers

N/A

N/A

$5955*

$8385*

 

N/A

N/A

$6355*

$8785*

See Offers

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6315*

$8885*

See Offers

N/A

N/A

$6315*

$8885*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$7075*

$9780*

See Offers

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6415*

$8985*

See Offers

N/A

N/A

$6415*

$8985*

 

N/A

N/A

$5855*

$8285*

See Offers

N/A

N/A

$5855*

$8285*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$6355*

$8785*

See Offers

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

See Offers

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

See Offers

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$7075*

$9780*

See Offers

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$7075*

$9780*

See Offers

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

See Offers

N/A

N/A

$6715*

$9285*

Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Eagle S

5.0
(2 Reviews)

2024 sail dates: Dec 29

2025 sail dates: Mar 31, Apr 14, Apr 28, May 12, Dec 12, More

$4880*
$697/night*
Oceanview
View Deal
$4880* dreamvacations.com $4880* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 30

2025 sail dates: Jul 16, Aug 27, Nov 05, More

$4415*
$631/night*
Balcony
View Deal
$4415* dreamvacations.com $4415* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$4415*

$6300*

See Offers

N/A

N/A

$4415*

$6300*

 

N/A

N/A

$4415*

$6300*

See Offers

N/A

N/A

$4415*

$6300*

 

N/A

N/A

$4915*

$6800*

See Offers

N/A

N/A

$4915*

$6800*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5995*

$8290*

See Offers

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

See Offers

N/A

N/A

$5275*

$7295*

Ports

  • WASHINGTON, D.C. USA
  • ANNAPOLIS, MARYLAND
  • ST. MICHAELS, MARYLAND
  • CAMBRIDGE, MARYLAND
  • RIVER CRUISING
  • Norfolk, Virginia
  • Williamsburg, Virginia
  • Mt Vernon, Virginia
View more ports

Ports

WASHINGTON, D.C. USA - ANNAPOLIS, MARYLAND - ST. MICHAELS, MARYLAND - CAMBRIDGE, MARYLAND - RIVER CRUISING - Norfolk, Virginia - Williamsburg, Virginia - Mt Vernon, Virginia - View more ports

American Legend S

2025 sail dates: Mar 15, Mar 25, Apr 04, Apr 14, Apr 24, May 04, May 14, More

2026 sail dates: May 22,

$8995*
$900/night*
Balcony
View Deal
$8995* dreamvacations.com $8995* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$8995*

$12175*

See Offers

N/A

N/A

$8995*

$12175*

 

N/A

N/A

$8995*

$12175*

See Offers

N/A

N/A

$8995*

$12175*

 

N/A

N/A

$8995*

$12175*

See Offers

N/A

N/A

$8995*

$12175*

 

N/A

N/A

$9595*

$12775*

See Offers

N/A

N/A

$9595*

$12775*

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • CRUISE SAN JUAN ISLANDS
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - CRUISE SAN JUAN ISLANDS - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Constellation S

4.9
(7 Reviews)

2025 sail dates: Apr 07, Apr 14, Apr 28, May 05, Sep 30, Oct 07, Oct 21, More

$4700*
$671/night*
Oceanview
View Deal
$4700* dreamvacations.com $4700* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 7 American Constellation reviews

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Constitution XL

5.0
(4 Reviews)

2025 sail dates: Apr 12, Apr 19, Apr 26, May 03, Sep 21, Sep 28, Oct 05, Oct 12, More

2026 sail dates: Mar 28, Apr 04, Apr 11, Apr 18, Apr 25, May 02, Sep 20, Sep 27, Oct 04, Oct 11, Oct 18, More

$4600*
$657/night*
Oceanview
View Deal
$4600* dreamvacations.com $4600* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 4 American Constitution reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

 

N/A

$5425*

$6240*

$8290*

See Offers

N/A

$5425*

$6240*

$8290*

 

N/A

$5425*

$6240*

$8290*

See Offers

N/A

$5425*

$6240*

$8290*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

 

N/A

$4700*

$5465*

$7395*

See Offers

N/A

$4700*

$5465*

$7395*

 

N/A

$4600*

$5365*

$7295*

See Offers

N/A

$4600*

$5365*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$4775*

$5490*

$7295*

See Offers

N/A

$4775*

$5490*

$7295*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

 

N/A

$5425*

$6240*

$8290*

See Offers

N/A

$5425*

$6240*

$8290*

 

N/A

$5425*

$6240*

$8290*

See Offers

N/A

$5425*

$6240*

$8290*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

 

N/A

$5100*

$5865*

$7795*

See Offers

N/A

$5100*

$5865*

$7795*

Ports

  • WASHINGTON, D.C. USA
  • Norfolk, Virginia
  • Williamsburg, Virginia
  • Yorktown, Virginia
  • Mt Vernon, Virginia
  • RIVER CRUISING
  • CAMBRIDGE, MARYLAND
  • ST. MICHAELS, MARYLAND
  • ANNAPOLIS, MARYLAND
View more ports

Ports

WASHINGTON, D.C. USA - Norfolk, Virginia - Williamsburg, Virginia - Yorktown, Virginia - Mt Vernon, Virginia - RIVER CRUISING - CAMBRIDGE, MARYLAND - ST. MICHAELS, MARYLAND - ANNAPOLIS, MARYLAND - View more ports

American Legend S

2025 sail dates:

2026 sail dates: Apr 12, May 02, May 12, More

$9020*
$902/night*
Balcony
View Deal
$9020* dreamvacations.com $9020* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9020*

$12010*

See Offers

N/A

N/A

$9020*

$12010*

 

N/A

N/A

$9595*

$12775*

See Offers

N/A

N/A

$9595*

$12775*

 

N/A

N/A

$9595*

$12775*

See Offers

N/A

N/A

$9595*

$12775*

51 - 60 of 125

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

More popular destinations for American Cruise Line

More popular cruise lines that sail to River Cruises - United States

More popular departure ports with sailings to River Cruises - United States