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American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

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125 cruises found

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Ports

  • BANGOR, MAINE
  • BELFAST, MAINE
  • Rockland, Maine
  • Bar Harbor, Maine
  • BATH, MAINE
  • CASTINE, MAINE
  • Boothbay, Maine
View more ports

Ports

BANGOR, MAINE - BELFAST, MAINE - Rockland, Maine - Bar Harbor, Maine - BATH, MAINE - CASTINE, MAINE - Boothbay, Maine - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates:

2026 sail dates:

$6210*
$887/night*
Oceanview
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$6210* luxuryonly.com $6210* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$6210*

$7335*

$9935*

 

N/A

$6210*

$7335*

$9935*

Ports

  • St. Louis, Missouri
  • Hannibal, Missouri
  • FORT MADISON, IOWA
  • DAVENPORT, IOWA
  • Dubuque, Iowa
  • Winona, Minnesota
  • Red Wing, Minnesota
  • St. Paul, Minnesota
View more ports

Ports

St. Louis, Missouri - Hannibal, Missouri - FORT MADISON, IOWA - DAVENPORT, IOWA - Dubuque, Iowa - Winona, Minnesota - Red Wing, Minnesota - St. Paul, Minnesota - View more ports

American Serenade S

2025 sail dates: Jul 12, Aug 09

2026 sail dates: Jul 11, Jul 25, Aug 08

$5135*
$734/night*
Balcony
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$5135* luxuryonly.com $5135* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5135*

$7295*

 

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$7795*

 

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Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Constellation S

4.9
(7 Reviews)

2026 sail dates: Mar 30, Apr 06, Apr 20, Apr 27, May 04, Sep 29, Oct 06, Oct 13, Oct 20, More

$4775*
$682/night*
Oceanview
View Deal
$4775* luxuryonly.com $4775* dreamvacations.com
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Read all 7 American Constellation reviews

Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Glory S

5.0
(1 Reviews)

2026 sail dates: Apr 11, Nov 25, Dec 09, Dec 23 More

$5630*
$804/night*
Oceanview
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$5630* luxuryonly.com $5630* dreamvacations.com
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Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$5990*

$6995*

$9315*

 

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$5990*

$6995*

$9315*

 

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$5630*

$6575*

$8755*

 

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$6575*

$8755*

 

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$6575*

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$6575*

$8755*

 

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$5630*

$6575*

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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Serenade S

2026 sail dates:

$5995*
$856/night*
Balcony
View Deal
$5995* luxuryonly.com $5995* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

Ports

  • HAYDEN ISLAND, PORTLAND, OREGON
  • Portland, Oregon
  • Astoria, Oregon
  • Mount St. Helens, Washington
  • Cruise Columbia River
  • THE DALLES, OREGON
  • Pendleton, Oregon
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Clarkston, Washington
View more ports

Ports

HAYDEN ISLAND, PORTLAND, OREGON - Portland, Oregon - Astoria, Oregon - Mount St. Helens, Washington - Cruise Columbia River - THE DALLES, OREGON - Pendleton, Oregon - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Clarkston, Washington - View more ports

American Jazz S

4.7
(8 Reviews)

2026 sail dates: May 02, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 08, Aug 22, Sep 05, Sep 19, Oct 03, Oct 17, Oct 31, More

$5995*
$856/night*
Balcony
View Deal
$5995* luxuryonly.com $5995* dreamvacations.com
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Top positive review

Top critical review

Read all 8 American Jazz reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5995*

$8290*

 

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$8290*

 

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$6355*

$8785*

 

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$8785*

 

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$6715*

$9285*

 

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$7075*

$9780*

 

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$9780*

 

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$9780*

 

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$9780*

 

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$6715*

$9285*

 

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Ports

  • Clarkston, Washington
  • Pendleton, Oregon
  • Cruise Columbia River
  • THE DALLES, OREGON
  • KALAMA, WASHINGTON
  • Astoria, Oregon
  • RIVER CRUISING
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - Pendleton, Oregon - Cruise Columbia River - THE DALLES, OREGON - KALAMA, WASHINGTON - Astoria, Oregon - RIVER CRUISING - Portland, Oregon - View more ports

American Pride S

4.4
(7 Reviews)

2026 sail dates: May 04, May 18, Jun 01, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 07, Sep 21, Oct 05, Oct 19, Nov 02, More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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Top critical review

Read all 7 American Pride reviews

Ports

  • Portland, Oregon
  • Astoria, Oregon
  • KALAMA, WASHINGTON
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Pendleton, Oregon
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - Astoria, Oregon - KALAMA, WASHINGTON - THE DALLES, OREGON - Cruise Columbia River - Pendleton, Oregon - Clarkston, Washington - View more ports

American Pride S

4.4
(7 Reviews)

2026 sail dates: Apr 27, May 11, May 25, Jun 08, Jun 22, Jul 06, Jul 20, Aug 03, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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Top critical review

Read all 7 American Pride reviews

Ports

  • Nashville, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Savannah, Tennessee
  • Florence, Alabama
  • Decatur, Alabama
  • Chattanooga, Tennessee
View more ports

Ports

Nashville, Tennessee - RIVER CRUISING - Paducah, Kentucky - Savannah, Tennessee - Florence, Alabama - Decatur, Alabama - Chattanooga, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2026 sail dates: Apr 29, May 13, May 27, Jun 10, Sep 16, Sep 30, Oct 14 More

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

 

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$4915*

$6800*

 

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$4915*

$6800*

 

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$5275*

$7295*

 

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Ports

  • Portland, Oregon
  • Astoria, Oregon
  • KALAMA, WASHINGTON
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Pendleton, Oregon
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - Astoria, Oregon - KALAMA, WASHINGTON - THE DALLES, OREGON - Cruise Columbia River - Pendleton, Oregon - Clarkston, Washington - View more ports

American West S

5.0
(1 Reviews)

2026 sail dates: May 04, Jun 01, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 07, Sep 21, Oct 05 More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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