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Jacksonville, Florida Cruises with American Cruise Line 9 cruises on American Cruise Line found

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Ports

  • Jacksonville, Florida
  • GREEN COVE SPRINGS, FL
  • PALATKA, FLORIDA
  • Amelia Island, Florida
  • ST. AUGUSTINE, FLORIDA
View more ports

Ports

Jacksonville, Florida - GREEN COVE SPRINGS, FL - PALATKA, FLORIDA - Amelia Island, Florida - ST. AUGUSTINE, FLORIDA - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates: Feb 03, Feb 24, Mar 03, Nov 21, Nov 28 More

2026 sail dates:

$4770*
$681/night*
Oceanview
View Deal
$4770* dreamvacations.com $4770* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4770*

$5655*

$7695*

See Offers

N/A

$4770*

$5655*

$7695*

 

N/A

$4770*

$5655*

$7695*

See Offers

N/A

$4770*

$5655*

$7695*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5630*

$6575*

$8755*

See Offers

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

See Offers

N/A

$5630*

$6575*

$8755*

Ports

  • Jacksonville, Florida
  • GREEN COVE SPRINGS, FL
  • PALATKA, FLORIDA
  • Amelia Island, Florida
  • ST. AUGUSTINE, FLORIDA
View more ports

Ports

Jacksonville, Florida - GREEN COVE SPRINGS, FL - PALATKA, FLORIDA - Amelia Island, Florida - ST. AUGUSTINE, FLORIDA - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates:

2026 sail dates: Jan 29, Feb 05, Feb 12, Feb 19, Feb 26, Mar 05, Mar 12, More

$4770*
$681/night*
Oceanview
View Deal
$4770* dreamvacations.com $4770* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4770*

$5655*

$7695*

See Offers

N/A

$4770*

$5655*

$7695*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • RIVER CRUISING
  • ST. AUGUSTINE, FLORIDA
  • Port Canaveral, Florida
  • West Palm Beach, Florida
  • KEY BISCAYNE, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
  • ST. PETERSBURG, FLORIDA
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - RIVER CRUISING - ST. AUGUSTINE, FLORIDA - Port Canaveral, Florida - West Palm Beach, Florida - KEY BISCAYNE, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - ST. PETERSBURG, FLORIDA - View more ports

American Pioneer S

2025 sail dates: Nov 01

2026 sail dates:

$12360*
$883/night*
Balcony
View Deal
$12360* dreamvacations.com $12360* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$12380*

$14530*

See Offers

N/A

N/A

$12380*

$14530*

 

N/A

N/A

$12360*

$14530*

See Offers

N/A

N/A

$12360*

$14530*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Eagle S

5.0
(2 Reviews)

2024 sail dates: Dec 22

2025 sail dates: Mar 10, Apr 07, Apr 21, May 05, Dec 05, More

$5030*
$719/night*
Oceanview
View Deal
$5030* dreamvacations.com $5030* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5630*

$6575*

$8755*

See Offers

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

See Offers

N/A

$5630*

$6575*

$8755*

 

N/A

$5030*

$5975*

$8155*

See Offers

N/A

$5030*

$5975*

$8155*

 

N/A

$5240*

$6245*

$8565*

See Offers

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$5240*

$6245*

$8565*

 

N/A

$5240*

$6245*

$8565*

See Offers

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$5240*

$6245*

$8565*

 

N/A

$5990*

$6995*

$9315*

See Offers

N/A

$5990*

$6995*

$9315*

 

N/A

$5630*

$6575*

$8755*

See Offers

N/A

$5630*

$6575*

$8755*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Independence S

4.6
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05,

$4110*
$587/night*
Oceanview
View Deal
$4110* dreamvacations.com $4110* luxuryonly.com
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Top positive review

Top critical review

Read all 8 American Independence reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4110*

$4990*

$6795*

See Offers

N/A

$4110*

$4990*

$6795*

 

N/A

$4425*

$5365*

$7295*

See Offers

N/A

$4425*

$5365*

$7295*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 28

2025 sail dates: Feb 15, Mar 01, Mar 15, Mar 29, Apr 26, May 10, Nov 15, Nov 29, Dec 13, Dec 27, More

$6245*
$892/night*
Balcony
View Deal
$6245* dreamvacations.com $6245* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$6575*

$8755*

See Offers

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N/A

$6575*

$8755*

 

N/A

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$6575*

$8755*

See Offers

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$6575*

$8755*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$6245*

$8565*

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$6245*

$8565*

 

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$6245*

$8565*

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$6245*

$8565*

 

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$6995*

$9315*

See Offers

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$6995*

$9315*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$8755*

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$6575*

$8755*

 

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$6575*

$8755*

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$6575*

$8755*

 

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$6995*

$9315*

See Offers

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$6995*

$9315*

 

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$6995*

$9315*

See Offers

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$6995*

$9315*

 

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$6995*

$9315*

See Offers

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$6995*

$9315*

 

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$6575*

$8755*

See Offers

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$6575*

$8755*

 

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$6575*

$8755*

See Offers

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$6575*

$8755*

 

N/A

N/A

$6575*

$8755*

See Offers

N/A

N/A

$6575*

$8755*

Ports

  • Jacksonville, Florida
  • GREEN COVE SPRINGS, FL
  • PALATKA, FLORIDA
  • Amelia Island, Florida
  • ST. AUGUSTINE, FLORIDA
View more ports

Ports

Jacksonville, Florida - GREEN COVE SPRINGS, FL - PALATKA, FLORIDA - Amelia Island, Florida - ST. AUGUSTINE, FLORIDA - View more ports

American Glory S

5.0
(1 Reviews)

2025 sail dates:

$5270*
$753/night*
Oceanview
View Deal
$5270* dreamvacations.com $5270* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5270*

$6155*

$8195*

See Offers

N/A

$5270*

$6155*

$8195*

Ports

  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • ST. SIMONS ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • RIVER CRUISING
  • Charleston, South Carolina
  • Wilmington, North Carolina
  • BEAUFORT, NORTH CAROLINA
  • KITTY HAWK, NORTH CAROLINA
  • Norfolk, Virginia
  • ST. MICHAELS, MARYLAND
  • Baltimore, Maryland
View more ports

Ports

Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - ST. SIMONS ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - RIVER CRUISING - Charleston, South Carolina - Wilmington, North Carolina - BEAUFORT, NORTH CAROLINA - KITTY HAWK, NORTH CAROLINA - Norfolk, Virginia - ST. MICHAELS, MARYLAND - Baltimore, Maryland - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates:

2026 sail dates:

$10585*
$756/night*
Oceanview
View Deal
$10585* dreamvacations.com $10585* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$10585*

$12360*

$16325*

See Offers

N/A

$10585*

$12360*

$16325*

Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • RIVER CRUISING
  • ST. AUGUSTINE, FLORIDA
  • Port Canaveral, Florida
  • West Palm Beach, Florida
  • KEY BISCAYNE, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
  • ST. PETERSBURG, FLORIDA
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - RIVER CRUISING - ST. AUGUSTINE, FLORIDA - Port Canaveral, Florida - West Palm Beach, Florida - KEY BISCAYNE, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - ST. PETERSBURG, FLORIDA - View more ports

American Patriot S

2025 sail dates: Nov 10

2026 sail dates:

$12360*
$883/night*
Balcony
View Deal
$12360* dreamvacations.com $12360* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$12380*

$16325*

See Offers

N/A

N/A

$12380*

$16325*

 

N/A

N/A

$12360*

$16325*

See Offers

N/A

N/A

$12360*

$16325*

1 - 9 of 9

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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More departure ports with American Cruise Line