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Santo Tomas De Castilla, Guatemala cruises 29 Santo Tomas De Castilla, Guatemala cruises

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29 cruises found

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Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Belize City, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Montego Bay, Jamaica
  • George Town, Grand Cayman
  • Key West, Florida
  • San Juan, Puerto Rico
  • Tortola, British Virgin Islands
  • Frederiksted, St. Croix, U.S.V.I.
  • Basseterre, St. Kitts
  • Pointe-A-Pitre, Guadeloupe
  • St. John's, Antigua
  • Charlotte Amalie, St. Thomas
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Belize City, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Montego Bay, Jamaica - George Town, Grand Cayman - Key West, Florida - San Juan, Puerto Rico - Tortola, British Virgin Islands - Frederiksted, St. Croix, U.S.V.I. - Basseterre, St. Kitts - Pointe-A-Pitre, Guadeloupe - St. John's, Antigua - Charlotte Amalie, St. Thomas - View more ports

Allura M

2026 sail dates:

$8999*
$375/night*
Balcony
View Deal
$8999* luxurycruiseconnections.com $8999* avoyatravel.com $10099* luxuryonly.com $10099* dreamvacations.com $8999* americandiscountcruises.com $8999* gotosea.com
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Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$8999*

$14699*

See Offers

N/A

N/A

$8999*

$14699*

 

N/A

$8999*

$10099*

$14699*

 

N/A

$8999*

$10099*

$14699*

See Offers

N/A

N/A

$8999*

$14699*

See Offers

N/A

N/A

$8999*

$14699*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Belize City, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Montego Bay, Jamaica
  • George Town, Grand Cayman
  • Key West, Florida
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Belize City, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Montego Bay, Jamaica - George Town, Grand Cayman - Key West, Florida - View more ports

Allura M

2026 sail dates:

$4799*
$400/night*
Balcony
View Deal
$4799* luxurycruiseconnections.com $4799* avoyatravel.com $5349* luxuryonly.com $5349* dreamvacations.com $4799* americandiscountcruises.com $4799* gotosea.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$4799*

$7799*

See Offers

N/A

N/A

$4799*

$7799*

 

N/A

$4799*

$5349*

$7799*

 

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$4799*

$5349*

$7799*

See Offers

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$4799*

$7799*

See Offers

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$4799*

$7799*

Ports

  • Belize City, Belize
  • DULCE RIVER (RIO DULCE), GUATEMALA
  • Santo Tomas De Castilla, Guatemala
  • LA ENSENADA, TELA, HONDURAS
  • Isla De Utila, Honduras
  • San Andres Island (Isla San Andres), Colombia
  • Puerto Limon, Costa Rica
  • Bocas Del Toro, Panama
  • Colon, Panama
View more ports

Ports

Belize City, Belize - DULCE RIVER (RIO DULCE), GUATEMALA - Santo Tomas De Castilla, Guatemala - LA ENSENADA, TELA, HONDURAS - Isla De Utila, Honduras - San Andres Island (Isla San Andres), Colombia - Puerto Limon, Costa Rica - Bocas Del Toro, Panama - Colon, Panama - View more ports

Le Champlain S

4.1
(3 Reviews)

2026 sail dates:

$7660*
$766/night*
Balcony
View Deal
$7660* luxurycruiseconnections.com $7730* luxuryonly.com $7730* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$7660*

$11710*

 

N/A

N/A

$7730*

$11710*

 

N/A

N/A

$7730*

$11710*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
  • Cartagena, Colombia
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Port Antonio, Jamaica
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Cartagena, Colombia - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Port Antonio, Jamaica - View more ports

Nautica S

4.1
(97 Reviews)

2026 sail dates:

$5699*
$285/night*
Inside
View Deal
$5699* luxurycruiseconnections.com $5699* avoyatravel.com $5699* luxuryonly.com $5699* dreamvacations.com $5699* americandiscountcruises.com $5699* gotosea.com
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Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports

Nautica S

4.1
(97 Reviews)

2026 sail dates:

$2999*
$300/night*
Inside
View Deal
$2999* luxurycruiseconnections.com $2999* avoyatravel.com $2999* luxuryonly.com $2999* dreamvacations.com $2999* americandiscountcruises.com $2999* gotosea.com
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Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Santo Tomas De Castilla, Guatemala
  • Belize City, Belize
  • Montego Bay, Jamaica
  • George Town, Grand Cayman
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Coxen Hole, Roatan, Bay Islands, Honduras - Santo Tomas De Castilla, Guatemala - Belize City, Belize - Montego Bay, Jamaica - George Town, Grand Cayman - View more ports

Allura M

2026 sail dates:

$4799*
$400/night*
Balcony
View Deal
$4799* luxurycruiseconnections.com $4799* avoyatravel.com $5349* luxuryonly.com $5349* dreamvacations.com $4799* americandiscountcruises.com $4799* gotosea.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$4799*

$7799*

See Offers

N/A

N/A

$4799*

$7799*

 

N/A

$4799*

$5349*

$7799*

 

N/A

$4799*

$5349*

$7799*

See Offers

N/A

N/A

$4799*

$7799*

See Offers

N/A

N/A

$4799*

$7799*

Ports

  • Miami, Florida
  • Key West, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Santo Tomas De Castilla, Guatemala
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Ocho Rios, Jamaica
  • George Town, Grand Cayman
View more ports

Ports

Miami, Florida - Key West, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Santo Tomas De Castilla, Guatemala - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Ocho Rios, Jamaica - George Town, Grand Cayman - View more ports

Seven Seas Grandeur M

4.1
(7 Reviews)

2026 sail dates:

$7599*
$633/night*
Suite
View Deal
$7599* luxurycruiseconnections.com $7599* avoyatravel.com $7599* luxuryonly.com $7599* dreamvacations.com $7599* gotosea.com
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Read all 7 Seven Seas Grandeur reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$7599*

See Offers

$21599*

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$7599*

 

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$7599*

 

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$7599*

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$7599*

Ports

  • Galveston, Texas
  • Cozumel, Mexico
  • Belize City, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Montego Bay, Jamaica
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
  • Miami, Florida
View more ports

Ports

Galveston, Texas - Cozumel, Mexico - Belize City, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Montego Bay, Jamaica - Willemstad, Curacao - Oranjestad, Aruba - Kralendijk, Bonaire - Miami, Florida - View more ports

Seven Seas Splendor M

4.4
(40 Reviews)

2026 sail dates:

$7599*
$543/night*
Suite
View Deal
$7599* luxurycruiseconnections.com $7599* luxuryonly.com $7599* dreamvacations.com $7599* gotosea.com
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Top critical review

Read all 40 Seven Seas Splendor reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$7599*

 

N/A

N/A

N/A

$7599*

 

N/A

N/A

N/A

$7599*

See Offers

N/A

N/A

N/A

$7599*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Santo Tomas De Castilla, Guatemala
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • George Town, Grand Cayman
  • Montego Bay, Jamaica
  • Great Stirrup Cay (Cruise Line Private Island), Bahamas
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Santo Tomas De Castilla, Guatemala - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Montego Bay, Jamaica - Great Stirrup Cay (Cruise Line Private Island), Bahamas - View more ports

Vista M

4.3
(41 Reviews)

2024 sail dates:

$3999*
$333/night*
Balcony
View Deal
$3999* oceaniacruises.com $3225* luxurycruiseconnections.com $4299* luxuryonly.com $4299* dreamvacations.com $3699* americandiscountcruises.com $3699* gotosea.com
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Top critical review

Read all 41 Vista reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$3999*

$6099*

 

N/A

N/A

$3225*

$4537*

 

N/A

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$4299*

$6049*

 

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$4299*

$6049*

See Offers

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$3699*

$6049*

See Offers

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$3699*

$6049*

21 - 29 of 29

All prices are per person based on double occupancy and do not include port/government fees and gratuities.