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Santo Domingo, Dominican Republic cruises 28 Santo Domingo, Dominican Republic cruises

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Ports

  • Cartagena, Colombia
  • Santo Domingo, Dominican Republic
  • Samana, Dominican Republic
  • Grand Turk Island
  • Nassau, Bahamas
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

Cartagena, Colombia - Santo Domingo, Dominican Republic - Samana, Dominican Republic - Grand Turk Island - Nassau, Bahamas - Ft. Lauderdale (Port Everglades), Florida - View more ports

Crystal Serenity XL

4.4
(104 Reviews)

2025 sail dates:

$4000*
$500/night*
Oceanview
View Deal
$4000* luxurycruiseconnections.com $4000* gotosea.com
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Read all 104 Crystal Serenity reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4000*

$4600*

$5000*

 

N/A

$4000*

$4600*

$5000*

Ports

  • Santo Domingo, Dominican Republic
  • Terre-De-Haut, Iles Des Saintes, Guadeloupe
  • Cabrits, Dominica
  • Pigeon Island, St. Lucia
  • Soufriere, St. Lucia
  • Tobago Cays, Grenadines
  • Mayreau, Grenadines
  • Port Elizabeth, Bequia, Grenadines
  • Union Island, Grenadines
  • Fort-De-France, Martinique
View more ports

Ports

Santo Domingo, Dominican Republic - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Cabrits, Dominica - Pigeon Island, St. Lucia - Soufriere, St. Lucia - Tobago Cays, Grenadines - Mayreau, Grenadines - Port Elizabeth, Bequia, Grenadines - Union Island, Grenadines - Fort-De-France, Martinique - View more ports

Le Bellot XL

4.9
(1 Reviews)

2026 sail dates:

$6410*
$641/night*
Balcony
View Deal
$6410* luxurycruiseconnections.com $6520* luxuryonly.com $6520* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$6410*

$10100*

 

N/A

N/A

$6520*

$10100*

 

N/A

N/A

$6520*

$10100*

Ports

  • San Juan, Puerto Rico
  • Cruz Bay, St. John, U.S.V.I.
  • St. John's, Antigua
  • Terre-De-Haut, Iles Des Saintes, Guadeloupe
  • Pigeon Island, St. Lucia
  • St. George's, Grenada
  • Gustavia, St. Barthelemy
  • Jost Van Dyke, B.V.I.
  • Prickly Pear Island, B.V.I.
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
  • Panama Canal Transit
  • Balboa, Panama
  • ISLA PARIDA, PANAMA
  • GOLFO DULCE, COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
  • Curu (Reserve), Costa Rica
  • Playas Del Coco, Costa Rica
  • Puerto Chiapas (Tapachula), Mexico
  • Huatulco, Mexico
  • Manzanillo, Mexico
  • Puerto Vallarta, Mexico
  • Seattle, Washington
  • Vancouver (Canada Place), British Columbia
  • Ketchikan, Alaska
  • Cruise Misty Fjords, Alaska
  • Wrangell, Alaska
  • Sitka, Alaska
  • Haines, Alaska
  • Juneau, Alaska
View more ports

Ports

San Juan, Puerto Rico - Cruz Bay, St. John, U.S.V.I. - St. John's, Antigua - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Pigeon Island, St. Lucia - St. George's, Grenada - Gustavia, St. Barthelemy - Jost Van Dyke, B.V.I. - Prickly Pear Island, B.V.I. - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - Curu (Reserve), Costa Rica - Playas Del Coco, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - Seattle, Washington - Vancouver (Canada Place), British Columbia - Ketchikan, Alaska - Cruise Misty Fjords, Alaska - Wrangell, Alaska - Sitka, Alaska - Haines, Alaska - Juneau, Alaska - View more ports

Star Seeker S

2026 sail dates:

$17843*
$364/night*
Suite
View Deal
$17843* luxurycruiseconnections.com $17843* luxuryonly.com $17843* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$17843*

 

N/A

N/A

N/A

$17843*

 

N/A

N/A

N/A

$17843*

Ports

  • San Juan, Puerto Rico
  • Cruz Bay, St. John, U.S.V.I.
  • St. John's, Antigua
  • Terre-De-Haut, Iles Des Saintes, Guadeloupe
  • Pigeon Island, St. Lucia
  • St. George's, Grenada
  • Gustavia, St. Barthelemy
  • Jost Van Dyke, B.V.I.
  • Prickly Pear Island, B.V.I.
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
  • Panama Canal Transit
  • Balboa, Panama
  • ISLA PARIDA, PANAMA
  • GOLFO DULCE, COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
View more ports

Ports

San Juan, Puerto Rico - Cruz Bay, St. John, U.S.V.I. - St. John's, Antigua - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Pigeon Island, St. Lucia - St. George's, Grenada - Gustavia, St. Barthelemy - Jost Van Dyke, B.V.I. - Prickly Pear Island, B.V.I. - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports

Star Seeker S

2026 sail dates:

$8538*
$356/night*
Suite
View Deal
$8538* luxurycruiseconnections.com $8643* luxuryonly.com $8643* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$8538*

 

N/A

N/A

N/A

$8643*

 

N/A

N/A

N/A

$8643*

Ports

  • San Juan, Puerto Rico
  • Cruz Bay, St. John, U.S.V.I.
  • St. John's, Antigua
  • Terre-De-Haut, Iles Des Saintes, Guadeloupe
  • Pigeon Island, St. Lucia
  • St. George's, Grenada
  • Gustavia, St. Barthelemy
  • Jost Van Dyke, B.V.I.
  • Prickly Pear Island, B.V.I.
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
View more ports

Ports

San Juan, Puerto Rico - Cruz Bay, St. John, U.S.V.I. - St. John's, Antigua - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Pigeon Island, St. Lucia - St. George's, Grenada - Gustavia, St. Barthelemy - Jost Van Dyke, B.V.I. - Prickly Pear Island, B.V.I. - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - View more ports

Star Seeker S

2026 sail dates:

$5684*
$334/night*
Suite
View Deal
$5684* luxurycruiseconnections.com $6143* luxuryonly.com $6143* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$5684*

 

N/A

N/A

N/A

$6143*

 

N/A

N/A

N/A

$6143*

Ports

  • San Juan, Puerto Rico
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
  • Balboa, Panama
  • Panama Canal Transit
  • ISLA PARIDA, PANAMA
  • GOLFO DULCE, COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
  • Curu (Reserve), Costa Rica
  • Playas Del Coco, Costa Rica
  • Puerto Chiapas (Tapachula), Mexico
  • Huatulco, Mexico
  • Manzanillo, Mexico
  • Puerto Vallarta, Mexico
View more ports

Ports

San Juan, Puerto Rico - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Balboa, Panama - Panama Canal Transit - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - Curu (Reserve), Costa Rica - Playas Del Coco, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - View more ports

Star Seeker S

2026 sail dates:

$8805*
$400/night*
Suite
View Deal
$8805* luxurycruiseconnections.com $8905* luxuryonly.com $8905* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$8805*

 

N/A

N/A

N/A

$8905*

 

N/A

N/A

N/A

$8905*

Ports

  • San Juan, Puerto Rico
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
  • Balboa, Panama
  • Panama Canal Transit
  • ISLA PARIDA, PANAMA
  • GOLFO DULCE, COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
View more ports

Ports

San Juan, Puerto Rico - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Balboa, Panama - Panama Canal Transit - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports

Star Seeker S

2026 sail dates:

$5880*
$420/night*
Suite
View Deal
$5880* luxurycruiseconnections.com $6005* luxuryonly.com $6005* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$5880*

 

N/A

N/A

N/A

$6005*

 

N/A

N/A

N/A

$6005*

Ports

  • San Juan, Puerto Rico
  • Catalina Island (Isla Catalina), Dominican Republic
  • Santo Domingo, Dominican Republic
  • Cartagena, Colombia
  • San Blas Islands, Panama
  • Colon, Panama
View more ports

Ports

San Juan, Puerto Rico - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - View more ports

Star Seeker S

2026 sail dates:

$3226*
$461/night*
Suite
View Deal
$3226* luxurycruiseconnections.com $3605* luxuryonly.com $3605* dreamvacations.com
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Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$3226*

 

N/A

N/A

N/A

$3605*

 

N/A

N/A

N/A

$3605*

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All prices are per person based on double occupancy and do not include port/government fees and gratuities.