Although there is no commercial vaccine available today for the norovirus, Takeda Pharmaceutical Company is investigating just such a vaccine. Trails are in progress now.   It would cut symptoms at least half or more and hopefully might be effective for more than a season. There are no real side affects except possible soreness at the injection site.  (Others are testing a nasal spray.)   If you were planning an ocean cruise, would you be interested in taking such a vaccine when available perhaps within a few years?

Here's a link for more information:

http://www.medscape.com/viewarticle/812143